Action of the jabuticaba peel extract (Plinia jaboticaba (Vell.) Kausel) in in vitro skin irritation and cytotoxicity

Autores

  • Bruna Santa Rosa
  • Vera Isaac

Resumo

The bark of jabuticaba represent an underutilized product in the industry, since, in most cases, they are
discarded after the use of the pulp. Starting from the concept that the peels are rich in several phenolic
compounds, vitamins and bioactive compounds, they therefore have an active potential to be used in
cosmetics. The aim of this study was to evaluate different cosmetic activities relevant to obtain a safe
and effective extract. For this, the extract was obtained through remaceration. Then, using in vitro
methodologies, cytotoxicity was evaluated using the MTT and NRU dyes with the cell line HaCat and
the potential for skin irritation due to the degradation of ovoalbumin was evaluated. The extract of the
bark of the jabuticaba showed an average cytotoxicity of 9.39 mg/mL and skin irritation rate of 0.8 to
1.6 mg/mL. Thus, our results direct the safe use of the extract of the bark of jabuticaba as a cosmetic
active.

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Publicado

2021-08-30

Como Citar

Santa Rosa, B., & Isaac, V. (2021). Action of the jabuticaba peel extract (Plinia jaboticaba (Vell.) Kausel) in in vitro skin irritation and cytotoxicity. ULAKES JOURNAL OF MEDICINE, 1(2). Recuperado de https://revistas.unilago.edu.br/index.php/ulakes/article/view/479